Key result
Resveratrol did not prevent or reverse the increase in blood pressure in NOS-inhibited rats (155.4 mmHg with resveratrol vs 149.5 mmHg with L-NNA alone).
Why the study?
Does resveratrol reduce blood pressure in rats with nitric oxide synthase-inhibited hypertension?
RCT (n=35)
Randomly divided
Does resveratrol reduce blood pressure in rats with nitric oxide synthase-inhibited hypertension?
Absolute Event Rate: 155.4% vs 149.5%
Resveratrol was unable to prevent or reverse blood pressure increase in a rat model of NOS-inhibited hypertension.
No takes yet. Share an insight, caveat, or question.
Resveratrol may attenuate HT in this NOS-inhibition rat model; leaves open clinical translation.
Aydın et al. (2017) conducted an RCT in Nitric oxide synthase-inhibited hypertension (n=35). Resveratrol vs. L-NNA alone was evaluated on Blood pressure at 10 days. Resveratrol did not prevent or reverse the increase in blood pressure in NOS-inhibited rats (155.4 mmHg with resveratrol vs 149.5 mmHg with L-NNA alone).
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