Streptomycin in the Treatment of Proteus Vulgaris Meningitis

Case Reports1 May 1950STREPTOMYCIN IN THE TREATMENT OF PROTEUS VULGARIS MENINGITISLEON ROSOVE, M.D., F.A.C.P., HAROLD E. WEST, M.D., ALBERT G. BOWER, M.D., F.A.C.P.LEON ROSOVE, M.D., F.A.C.P.Search for more papers by this author, HAROLD E. WEST, M.D.Search for more papers by this author, ALBERT G. BOWER, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-32-5-960 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptProteus vulgaris meningitis is relatively uncommon. It may occur by direct extension from an adjacent otitis media or mastoiditis and occasionally as a complication of septicemia from a focus of infection, usually in the genito-urinary tract. The causative organism is a gram-negative, aerobic, non-sporulating, actively motile bacterium, usually occurring as a saprophytic non-pathogen in the upper respiratory, gastrointestinal, or genito-urinary tracts. Occasionally it produces severe infection and death.In a review of the literature Abrams1states that approximately four-fifths of patients under 40 years of age withProteus vulgarissepticemia had middle ear infection and of those over 40 years...Bibliography1. Abrams HL: Septicemia due to Proteus vulgaris. Review of the literature and report of a case cured by streptomycin, New England J. Med. 238: 185-187, 1948. CrossrefMedlineGoogle Scholar2. , J. A. M. A. 132: 70, 1946. CrossrefGoogle Scholar3. Paine TF: Streptomycin in the treatment of certain gram-negative bacillus infections of the central nervous system, Am. J. M. Sc. 213: 676-685, 1947. CrossrefMedlineGoogle Scholar4. KaplanPoweleit MZAC: Proteus vulgaris meningitis, Am. J. Dis. Child. 77: 454-459, 1949. MedlineGoogle Scholar5. Abraham EP: Further observations on penicillin, Lancet 2: 177-188, 1941. CrossrefGoogle Scholar6. Fleming A: On the antibacterial action of cultures of a penicillium, etc., Brit. J. Exper. Path. 10: 226-236, 1929. Google Scholar7. HelmholzSurg HFC: Bacterial action of penicillin commonly present in infections of the urinary tract, Am. J. Dis. Child. 68: 236-242, 1944. CrossrefGoogle Scholar8. JeffreyThomson JSS: Penicillin in battle casualties, British M. J. 2: 1-4, 1944. CrossrefMedlineGoogle Scholar9. Buggs CW: The in vitro action of streptomycin on bacteria, J. A. M. A. 130: 64-67, 1946. CrossrefMedlineGoogle Scholar10. Knop CQ: Experimental study of the development of resistance to streptomycin by some bacteria commonly found in urinary infections, Proc. Staff Meet., Mayo Clin. 21: 273-276, 1946. MedlineGoogle Scholar11. Reiman HA: Streptomycin for certain systemic infections and its effect on the urinary and fecal flora, Arch. Int. Med. 76: 269-277, 1945. CrossrefGoogle Scholar12. OrdalMeyer ZJE: The effect of streptomycin on proteus infections of the chick embryo, Jr. Bact. 52: 67-70, 1946. CrossrefGoogle Scholar13. Collins HS: Aureomycin—a new antibiotic, Ann. Int. Med. 29: 1077-1092, 1948. LinkGoogle Scholar14. Gottlieb D: Some properties of antibiotic obtained from species of streptomyces, Jr. Bact. 55: 409-417, 1948. CrossrefGoogle Scholar15. Smith RM: Chloromycetin: biological studies, Jr. Bact. 55: 425-448, 1948. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: *Received for publication July 28, 1949.From the University of Southern California School of Medicine and the Communicable Disease Unit of the Los Angeles County General Hospital. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byProteus mirabilis meningitis: Report of two cases treated with ampicillin 1 May 1950Volume 32, Issue 5Page: 960-964KeywordsEar infectionsGastrointestinal tractHospital medicineMeningitisOtitis mediaSepsisStreptomycin ePublished: 1 December 2008 Issue Published: 1 May 1950 PDF downloadLoading ...