Key result
Isoflurane anaesthesia in children resulted in a mean time to loss of consciousness of 1.5 minutes and a faster mean elimination half-time compared to halothane (54 vs 220 seconds).
Why the study?
Does isoflurane improve induction and recovery times compared to halothane in children undergoing anaesthesia?
Population
248 children undergoing anaesthesia
Comparison
Isoflurane anaesthesia vs Halothane (in a subset of 9 children)
Design
Cohort
Authors
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Isoflurane may facilitate quicker pediatric induction and recovery; extends observational pharmacokinetic data but leaves open randomized outcome confirmation.
Observational (n=248)
Does isoflurane improve induction and recovery times compared to halothane in children undergoing anaesthesia?
Isoflurane provides rapid induction and recovery in pediatric anesthesia, with faster elimination compared to halothane.
WREN et al. (1985) conducted an observational in Paediatric anaesthesia (n=248). Isoflurane vs. Halothane was evaluated on Time to loss of consciousness and elimination half-time. Isoflurane anaesthesia in children resulted in a mean time to loss of consciousness of 1.5 minutes and a faster mean elimination half-time compared to halothane (54 vs 220 seconds).
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