Why the study?
Does a feedback-regulated ultrafiltration algorithm allow continuous measurement of absolute plasma refill rate in hypotension-prone hemodialysis patients?
Population
5 hypotension-prone hemodialysis patients
Design
Case_series
Follow-up
During dialysis (at least 2 hours)
Key result
Continuous measurement of absolute plasma refill rate during hemodialysis showed a significant decrease in the first hour from 21 to 9 ml/min (p<0.05), which was unaffected by AES or HAES.
Authors
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Early plasma refill decline observed via feedback ultrafiltration in one case; hypothesis-generating for refining dry weight targets in hypotension-prone hemodialysis.
Does a feedback-regulated ultrafiltration algorithm allow continuous measurement of absolute plasma refill rate in hypotension-prone hemodialysis patients?
p-value: p=< 0.05
Continuous, online measurement of refill patterns using feedback-regulated ultrafiltration reveals a rapid fall in refill during early dialysis, which may help accurately estimate dry weight.
Brummelhuis et al. (2008) studied Hemodialysis with hypotension proneness (n=5). Feedback regulated ultrafiltration, antiembolism stockings (AES), and hydroxy-ethylated starch (HAES) was evaluated on Absolute plasma refill rate (p=< 0.05). Continuous measurement of absolute plasma refill rate during hemodialysis showed a significant decrease in the first hour from 21 to 9 ml/min (p<0.05), which was unaffected by AES or HAES.