Key result
A literature review prompted by a 15-year late relapse of retroperitoneal liposarcoma emphasizes that extensive surgery is the mainstay of treatment and indefinite prolonged surveillance is required.
Retroperitoneal liposarcomas require extensive surgery and indefinite prolonged surveillance due to high risk of late local recurrence.
Answers are grounded in this paper and cite their sources.
Rare late retroperitoneal liposarcoma relapse after 15 years signals need for extended surveillance; leaves open optimal follow-up duration.
Soft tissue sarcomas (STS) are rare and heterogeneous tumours representing approximately 0.7%-1% of all adult tumours. In the adults and among the retroperitoneal sarcomas (RPS), Liposarcoma (LS) is the most common variant accounting for 12% -20% of all sarcomas and up to 45% of sarcomas at retroperitoneal localization. A rare case of LS relapsed after 15 years is giving the occasion to review the published literature and emphasise the followings concepts: 1) Despite extensive surgery remains the mainstay of treatment for localized STS at present, anatomical complexity and occult localization result in local recurrence in the majority of patients; 2) The role of imaging and tumour markers is still limited; 3) Indefinite prolonged surveillance is a key point of treatment; 4) Referral to tertiary centres with dedicated Retroperitonal Surgeons and Oncology expertise is mandatory.
No takes yet. Share an insight, caveat, or question.
Pisani et al. (2015) conducted a review in Retroperitoneal Liposarcoma (n=1). A literature review prompted by a 15-year late relapse of retroperitoneal liposarcoma emphasizes that extensive surgery is the mainstay of treatment and indefinite prolonged surveillance is required.
Synapse has enriched 10 related papers. Consider them for comparative context: