Key result
Pre-surgical depression symptoms were associated with a 13.7% increased hazard of death or major adverse cardiac events per 1-point increment on the Beck Depression Inventory.
Why the study?
Do pre-surgical depression and anxiety symptoms predict recovery outcomes (pain, physical symptoms, emergency admissions, death/MACE) in patients undergoing elective CABG surgery?
Cohort (n=251)
No
Do pre-surgical depression and anxiety symptoms predict recovery outcomes (pain, physical symptoms, emergency admissions, death/MACE) in patients undergoing elective CABG surgery?
Pre-operative anxiety predicts self-reported pain and physical symptoms at 12 months, whereas pre-operative depression predicts objective clinical outcomes like emergency admissions and death/MACE up to 2.68 years after CABG surgery.
Answers are grounded in this paper and cite their sources.
May support pre-surgical depression screening; leaves open whether intervention reduces cardiac events.
We aimed to explore the combined contribution of pre-surgical depression and anxiety symptoms for recovery following coronary artery bypass graft (CABG) using data from 251 participants. Participants were assessed prior to surgery for depression and anxiety symptoms and followed up at 12 months to assess pain and physical symptoms, while hospital emergency admissions and death/major adverse cardiac events (MACE) were monitored on average 2.68 years after CABG. After controlling for covariates, baseline anxiety symptoms, but not depression, were associated with greater pain (β = 0.231, p = 0.014) and greater physical symptoms (β = 0.194, p = 0.034) 12 months after surgery. On the other hand, after controlling for covariates, baseline depression symptoms, but not anxiety, were associated with greater odds of having an emergency admission (OR 1.088, CI 1.010-1.171, p = 0.027) and greater hazard of death/MACE (HR 1.137, CI 1.042-1.240, p = 0.004). These findings point to different pathways linking mood symptoms with recovery after CABG surgery.
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Poole et al. (2016) conducted a cohort in Coronary artery bypass graft (CABG) surgery (n=251). Pre-surgical depression symptoms vs. Lower depression symptoms was evaluated on Death or major adverse cardiac events (MACE) (HR 1.137, 95% CI 1.042-1.240, p=0.004). Pre-surgical depression symptoms were associated with a 13.7% increased hazard of death or major adverse cardiac events per 1-point increment on the Beck Depression Inventory.
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