Key result
An 81-year-old woman with Takotsubo cardiomyopathy complicated by ventricular septal perforation developed fatal ventricular fibrillation three days after hospitalization despite inotrope treatment.
Case Report (n=1)
Takotsubo cardiomyopathy complicated by ventricular septal perforation is a rare, critical condition that can lead to fatal ventricular arrhythmias, highlighting the need for careful QT interval monitoring and cautious inotrope use.
Rare Takotsubo case with ventricular shunt; leaves open prevalence, prognosis, and management implications.
An 81-year-old woman was admitted with chest pain. An electrocardiogram demonstrated ST segment elevation in leads II, III and aVF, and echocardiography revealed left ventricular apical asynergy with a left-to-right ventricular shunt. Meanwhile, emergent coronary angiography showed no significant coronary artery stenosis, whereas left ventriculography indicated apical ballooning and a left-to-right ventricular shunt. We therefore diagnosed the patient with Takotsubo cardiomyopathy complicated by ventricular septal perforation and cardiogenic shock. An electrocardiogram disclosed a prolonged QT interval over time, and the patient became hemodynamically stable under treatment with inotropes; however, she suddenly developed fatal ventricular fibrillation three days after hospitalization. Takotsubo cardiomyopathy complicated by ventricular septal perforation is a critical condition that requires careful monitoring.
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Aikawa et al. (2015) conducted a case report in Takotsubo cardiomyopathy complicated by ventricular septal perforation (n=1). Inotropes was evaluated on Fatal ventricular fibrillation. An 81-year-old woman with Takotsubo cardiomyopathy complicated by ventricular septal perforation developed fatal ventricular fibrillation three days after hospitalization despite inotrope treatment.
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