Answers are grounded in this paper and cite their sources.
Indospicine (1), the hepatotoxic amino acid from Indigofera spicata Forsk. is synthesized from 2-amino-6-hydroxyhexanoic acid (6- hydroxynorleucine) by stepwise replacement of hydroxyl by tosyloxy, cyano, imidoester, and amidine groupings.
No takes yet. Share an insight, caveat, or question.
Culvenor et al. (1971) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: