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The reaction of diethylzinc with a range of arenecarbaldehydes has been catalysed by N-alkyl ephedrines to give 1-arylpropan-1-ols with good to excellent optical yields. The enantioselectivity of the reaction was substantially improved by the use of a 4 molar excess of the organozinc reagent.
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Chaloner et al. (1991) studied this question.
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