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A physiological method of estimating the number of motor units in normal and dystrophic muscles has revealed a large reduction in the number of motor units in dystrophic muscles. Anatomical confirmation of the results has been obtained. Dystrophic muscles also exhibit a `myasthenic-like' response to high frequency stimulation. It is suggested that the nerve fibre is primarily affected in murine dystrophy.
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Harris et al. (1971) studied this question.
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