Key result
Late dinner and skipping breakfast were associated with an increased risk of proteinuria onset.
Why the study?
The relationship between dietary habits and the development of chronic kidney disease is unclear.
Do unhealthy dietary habits increase the risk of proteinuria onset in a general population aged ≥40 years?
Cohort (n=26,764)
Do unhealthy dietary habits increase the risk of proteinuria onset in a general population aged ≥40 years?
Late dinner and skipping breakfast are associated with a higher risk of developing proteinuria, a key prognostic factor for chronic kidney disease.
Answers are grounded in this paper and cite their sources.
Late dinner and skipping breakfast were associated with proteinuria onset; hypothesis-generating observation warrants prospective trials before guiding prevention strategies.
The relationship between dietary habits and development of chronic kidney disease (CKD) is unclear. This retrospective cohort study was conducted to examine the association between unhealthy dietary habits and proteinuria onset, a key prognostic factor of CKD, among a Japanese general population aged ≥40 years. The risks of proteinuria onset were estimated based on the status of baseline unhealthy dietary habits (quick eating, late dinner, late evening snack, and skipping breakfast) compared with the status without these habits. A total of 26,764 subjects were included, with a mean follow-up period of 3.4 years. The most frequent unhealthy dietary habit was quick eating (29%), followed by late dinner (19%), late evening snack (16%), and skipping breakfast (9%). During the follow-up period, 10.6% of participants developed proteinuria. Late dinner and skipping breakfast showed an increased adjusted risk of proteinuria onset (hazard ratio (HR) 1.12, 95% confidence interval (CI) 1.02 to 1.22, and HR 1.15, 95% CI 1.01 to 1.31, respectively). Unhealthy dietary habits were not associated with changes in body mass index or waist-to-height ratio during the follow-up period. Our results suggest that late dinner and skipping breakfast are associated with higher risks for proteinuria onset.
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Tokumaru et al. (2020) conducted a cohort in Chronic kidney disease (proteinuria) (n=26,764). Unhealthy dietary habits (late dinner and skipping breakfast) vs. Status without these habits was evaluated on Proteinuria onset (HR 1.12, 95% CI 1.02-1.22). Late dinner and skipping breakfast were associated with an increased risk of proteinuria onset.
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