Key result
Aortic valve neocuspidization using autologous pericardium provides excellent hemodynamics and low pacemaker rates, but requires more data on long-term durability.
Why the study?
To describe the technique of aortic valve neocuspidization using autologous pericardium (Ozaki procedure) in adult cardiac surgery, analyze recent findings, and discuss its benefits and limitations.
The Ozaki procedure is a promising alternative to standard aortic valve replacement offering several hemodynamic and clinical benefits, but careful patient selection is recommended due to limited long-term durability data.
May support AVNeo in anticoagulation-averse patients; leaves open durability and superiority versus standard valves in randomized trials.
Purpose of the Review The aim of this article is to describe the technique of aortic valve neocuspidization using autologous pericardium (AVNeo, “OZAKI procedure”) in adult cardiac surgery, to analyze recent findings, and to discuss benefits and limitations of this technique. Recent Findings Potential benefits of this technique include excellent hemodynamic performances, minimal use of foreign material, low rates of permanent pacemaker implantation, and omission of oral anticoagulation. However, data regarding the durability of the procedure are hitherto limited, and the procedure is associated with a higher complexity compared to aortic valve replacement. Summary AVNeo using autologous pericardium in adult cardiac surgery is a promising technique providing several benefits. However, there is a major unmet need for more data, especially regarding long-term durability. Thus, based on currently available data, we recommend careful patient selection within the heart team and shared decision-making with the informed patient.
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Koechlin et al. (2021) conducted a review in Aortic valve disease. Aortic valve neocuspidization using autologous pericardium (Ozaki procedure) vs. Aortic valve replacement was evaluated. Aortic valve neocuspidization using autologous pericardium provides excellent hemodynamics and low pacemaker rates, but requires more data on long-term durability.
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