Key result
Apelin acts as a beneficial adipokine that improves glucose uptake and insulin sensitivity, and its elevated plasma concentrations in obesity and type 2 diabetes may be a compensatory mechanism.
Apelin is a novel adipokine that regulates glucose and lipid metabolism, and its elevated levels in obesity and type 2 diabetes may represent a compensatory mechanism to decrease insulin resistance.
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Apelin's adipokine role may expand cardiometabolic targets; leaves open clinical translation and mechanisms.
Bertrand et al. (2015) conducted a review in Obesity and Type 2 Diabetes. Apelin was evaluated. Apelin acts as a beneficial adipokine that improves glucose uptake and insulin sensitivity, and its elevated plasma concentrations in obesity and type 2 diabetes may be a compensatory mechanism.
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