Why the study?
Recent advances have made catheter-directed treatment a viable therapeutic option for acute pulmonary embolism, prompting the need to define its role alongside organizational and therapeutic aspects of patient care.
Catheter-directed therapies are recommended as a viable alternative to surgical embolectomy for high-risk acute pulmonary embolism when systemic thrombolysis is contraindicated or ineffective, and for intermediate-high-risk patients deteriorating on anticoagulation.
May support consideration of catheter-directed therapy in high-risk PE when thrombolysis contraindicated; leaves open need for randomized comparisons.
Thanks to advances in interventional cardiology technologies, catheter-directed treatment has become recently a viable therapeutic option in the treatment of patients with acute pulmonary embolism at high risk of early mortality. Current transcatheter techniques allow for local fibrinolysis or embolectomy with minimal risk of complications. Therefore, these procedures can be considered in high-risk patients as an alternative to surgical pulmonary embolectomy when systemic thrombolysis is contraindicated or ineffective. They are also considered in patients with intermediate-high-risk pulmonary embolism who do not improve or deteriorate clinically despite anticoagulation. The purpose of this article is to present the role of transcatheter techniques in the treatment of patients with acute pulmonary embolism. We describe current knowledge and expert opinions in this field. Interventional treatment is described in the broader context of patient care organization and therapeutic modalities. We present the organization and responsibilities of pulmonary embolism response team, role of pre-procedural imaging, periprocedural anticoagulation, patient selection, timing of intervention, and intensive care support. Currently available catheter-directed therapies are discussed in detail including standardized protocols and definitions of procedural success and failure. This expert opinion has been developed in collaboration with experts from various Polish scientific societies, which highlights the role of teamwork in caring for patients with acute pulmonary embolism.
No takes yet. Share an insight, caveat, or question.
Kopeć et al. (2023) conducted a review in Acute pulmonary embolism. Catheter-directed therapies was evaluated. Catheter-directed therapies provide a viable alternative to surgical embolectomy for patients with acute high-risk pulmonary embolism when systemic thrombolysis is contraindicated or ineffective.
Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context: