Key result
Muscle metaboreflex activation increased heart rate in the seated (Δ 4 beats/min) but not supine position (Δ -1 beats/min); this response was abolished by β1-adrenergic blockade.
Why the study?
Does body position modulate sympathetically mediated cardiac responses to isolated muscle metaboreflex activation following exercise in healthy men?
Population
13 healthy men (mean age 21 ± 3 yr)
Comparison
Posthandgrip exercise ischemia in the seated… vs Posthandgrip exercise ischemia in the supine…
Design
Other, Four trials were randomly conducted
Authors
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Body position modulates metaboreflex heart rate responses in healthy men; leaves open clinical translation and relevance in disease.
RCT (n=13)
Randomized
Does body position modulate sympathetically mediated cardiac responses to isolated muscle metaboreflex activation following exercise in healthy men?
Absolute Event Rate: 4% vs -1%
Sympathetically mediated cardiac responses to isolated muscle metaboreflex activation after exercise are modulated by body position and central blood volume mobilization.
Teixeira et al. (2017) conducted an RCT in Healthy (n=13). Seated position and β1-adrenergic blockade vs. Supine position and control conditions was evaluated on Change in heart rate from baseline during posthandgrip exercise ischemia. Muscle metaboreflex activation increased heart rate in the seated (Δ 4 beats/min) but not supine position (Δ -1 beats/min); this response was abolished by β1-adrenergic blockade.
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