Key result
Graded muscle metaboreflex activation via post-exercise ischemia did not significantly alter carotid-cardiac baroreflex maximal gain compared to rest (-0.49 vs -0.51 beats/min/mmHg; P>0.05).
Why the study?
Does graded muscle metaboreflex activation influence carotid-cardiac baroreflex responsiveness in healthy humans?
Population
8 healthy subjects, mean age 24 +/- 1 years
Comparison
Graded isolation of the muscle metaboreflex… vs Rest
Design
Other
Authors
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Preserves baroreflex gain estimates during metaboreflex activation; extends resetting data but leaves open relevance in disease.
Does graded muscle metaboreflex activation influence carotid-cardiac baroreflex responsiveness in healthy humans?
Absolute Event Rate: -0.49% vs -0.51%
p-value: p=>0.05
Muscle metaboreflex activation contributes to the resetting of the carotid baroreflex control of heart rate but does not alter its responsiveness in humans.
Fisher et al. (2008) studied Healthy (n=8). Graded muscle metaboreflex activation via post-exercise ischemia vs. Rest was evaluated on Operating point gain and maximal gain of the carotid-cardiac baroreflex function curve (p=>0.05). Graded muscle metaboreflex activation via post-exercise ischemia did not significantly alter carotid-cardiac baroreflex maximal gain compared to rest (-0.49 vs -0.51 beats/min/mmHg; P>0.05).
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