Key result
Low-dose amiodarone therapy achieved overall successful use (satisfactory arrhythmia control and freedom from side effects) in 67%, 59%, and 53% of patients at 1, 2, and 3 years, respectively.
Why the study?
Does low-dose oral amiodarone therapy provide effective arrhythmia control with an acceptable safety profile in patients with symptomatic drug-refractory or life-threatening arrhythmias?
Cohort (n=124)
Does low-dose oral amiodarone therapy provide effective arrhythmia control with an acceptable safety profile in patients with symptomatic drug-refractory or life-threatening arrhythmias?
Long-term low-dose amiodarone therapy provides effective control of refractory tachyarrhythmias with a manageable side effect profile and low rates of drug withdrawal.
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May support low-dose amiodarone in refractory arrhythmias; leaves open randomized confirmation of long-term efficacy and safety.
LEE et al. (1997) conducted a cohort in Symptomatic drug-refractory or life-threatening arrhythmias (n=124). Low-dose oral amiodarone therapy was evaluated on Overall successful use of amiodarone (satisfactory arrhythmia control and freedom from side effects) at 1 year. Low-dose amiodarone therapy achieved overall successful use (satisfactory arrhythmia control and freedom from side effects) in 67%, 59%, and 53% of patients at 1, 2, and 3 years, respectively.
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