Key result
Adequate intravenous acyclovir administration within 24 hours of disease onset is crucial for the successful management of chickenpox in pediatric patients.
This review summarizes the clinical manifestations, complications, and management strategies for chickenpox in pediatric patients, emphasizing the importance of timely acyclovir administration.
May support timely acyclovir in pediatric varicella; leaves open need for randomized confirmation.
Chickenpox can be defined as a highly communicable viral infection caused by varicella zoster virus; most frequently influences pediatric in five to nine yrs old. The commonly occurred signs and symptoms of chickenpox are comprises vesicular rash appears on the scalp, face and trunk, and then disseminates distally to limbs (centrifugal distribution). The most common complications of chickenpox are bacterial soft-tissue infection, pneumonia, and encephalitis. Encephalitis is a most commonly occurred central nervous system complications expose the pediatric to other problems or death. The main goal chickenpox infection management in children is to alleviate the symptoms such as skin infections, fever, itching etc and making the children confortable. Adequate intravenous acyclovir administration is crucial for successful management of chickenpox, but it must be administered within twenty-four hrs. after the onset of the disease. Management of chickenpox with oral acyclovir given within twenty four hrs of onset of rash may be more effective.
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Gudisa Bereda (2022) conducted a review in Chickenpox infection. Chickenpox management (Acyclovir, symptomatic treatment) was evaluated. Adequate intravenous acyclovir administration within 24 hours of disease onset is crucial for the successful management of chickenpox in pediatric patients.
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