The Pathway of Infection in Poliomyelitis

Editorial1 August 1941THE PATHWAY OF INFECTION IN POLIOMYELITISP. W. C.P. W. C.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-15-2-329 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe problem of the pathogenesis of poliomyelitis—its portal of entry, the manner of the distribution of the virus in the body tissues and the route by which it is disseminated—has not yet been satisfactorily solved, in spite of much intensive investigation.The study of the disease is beset with many practical difficulties. One of the greatest of these is the fact that the monkey is the only animal susceptible to the filtrable virus which causes the disease, and successful inoculation of these animals is the only method of demonstrating its presence. Even monkeys appear to differ in susceptibility, and individual...1 LEVADITIKLINGHORNUS CCG: Transmission expérimentale de la poliomyélite par la voie digestive, Compt. rend. Soc. de biol., 1933, cxii, 43-45. Google Scholar2 FLEXNER S: Respiratory versus gastrointestinal infection in poliomyelitis, Jr. Exper. Med., 1936, lxiii, 209-226. CrossrefGoogle Scholar3 TRASKPAULVIGNEC JDJRAJ: I. Poliomyelitic virus in human stools, Jr. Exper. Med., 1940, lxxi, 751-764. CrossrefGoogle Scholar4 PAULTRASKGARD JRJDS: II. Poliomyelitic virus in urban sewage, Jr. Exper. Med., 1940, lxxi, 765-778. CrossrefGoogle Scholar5 SABINWARD ABR: The natural history of human poliomyelitis. I. Distribution of virus in nervous and non-nervous tissues, Jr. Exper. Med., 1941, lxxiii, 771-794. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 August 1941Volume 15, Issue 2Page: 329-332KeywordsInoculationPathogenesisPoliomyelitis ePublished: 1 December 2008 Issue Published: 1 August 1941 PDF downloadLoading ...