November 1, 2011Seminars in Reproductive Medicine
Testing for Inherited Thrombophilia in Recurrent Miscarriage
Key result
Routine testing for inherited thrombophilia in women with recurrent miscarriage is not recommended as evidence does not show that anticoagulants improve the chance of live birth.
Why the study?
Does testing for inherited thrombophilia and subsequent anticoagulant use improve the chance of live birth in women with recurrent miscarriage?
Population
Women with recurrent miscarriage
Design
Review
Authors
Discussion
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Member takes
Implication
May reduce low-value testing and anticoagulation in recurrent miscarriage; confirms no live birth benefit in current evidence.
Structured PICO
Does testing for inherited thrombophilia and subsequent anticoagulant use improve the chance of live birth in women with recurrent miscarriage?
P
Population
Women with recurrent miscarriage
I
Intervention
Testing for inherited thrombophilia (and subsequent use of anticoagulants)
O
Outcome
Live birthhard clinical
Routine testing for inherited thrombophilia in women with recurrent miscarriage is not recommended because there is no evidence that anticoagulant treatment improves live birth rates.
Cite This Study
Jong et al. (2011) conducted a review in Recurrent miscarriage. Testing for inherited thrombophilia was evaluated. Routine testing for inherited thrombophilia in women with recurrent miscarriage is not recommended as evidence does not show that anticoagulants improve the chance of live birth.