Key result
Coronary artery calcium scoring is highlighted as a cost-effective and specific marker to optimize ASCVD risk stratification and guide preventive therapies in South Asian individuals.
Why the study?
South Asian individuals face an elevated risk for ASCVD and related mortality, highlighting the need to evaluate whether coronary artery calcium scoring can improve risk stratification and guide preventive therapies in this population.
Does coronary artery calcium (CAC) scoring improve cardiovascular risk stratification in South Asian individuals?
Does coronary artery calcium (CAC) scoring improve cardiovascular risk stratification in South Asian individuals?
Coronary artery calcium scoring is a valuable tool for optimizing cardiovascular risk stratification and guiding preventive therapies in high-risk South Asian populations.
May inform ASCVD stratification in South Asians; hypothesis-generating without dedicated outcome trials.
South Asian (SA) individuals, particularly those that reside in the United States and other Westernized countries, are at an elevated risk for ASCVD and mortality related to ASCVD. The 2018 ACC/AHA/Multi-society Cholesterol guideline listed SA as a high-risk ethnicity, underscoring the importance of treating modifiable risk factors to reduce ASCVD burden. Coronary artery calcium (CAC), a highly specific marker of subclinical atherosclerosis, may be a useful test to improve risk stratification among SA individuals. CAC testing is a cost-effective, highly reproducible, and specific marker of subclinical atherosclerosis, shown to improve ASCVD risk assessment across all racial/ethnic groups, thereby serving as a guide for initiating or deferring preventive therapies. In this White Paper we will discuss the use of CAC scoring to optimize risk stratification and delivery of preventive therapies to individuals of SA ethnicity.
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Agarwala et al. (2022) conducted a review in Atherosclerotic cardiovascular disease (ASCVD) risk. Coronary artery calcium (CAC) scoring was evaluated. Coronary artery calcium scoring is highlighted as a cost-effective and specific marker to optimize ASCVD risk stratification and guide preventive therapies in South Asian individuals.
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