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Rationale: Up to 20% of percutaneous intervention (PCI) procedures are challenged by severe calcification, lesion calcification increases procedural complexity and time. S-IVL is supposed to be less effective in vessel size greater than or equal to 3.5 mm and lesions with eccentric calcium. S-IVL devices apply localized pulsatile sonic pressure waves that pass through the soft tissue and modify and fracture the underlying calcium. In literature, S-IVL is found to be useful when the calcium is circumferential and superficial as well as deep. It's efficacy in large vessel diameter and eccentric calcium is questionable.
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Debabrata et al. (2021) studied this question.
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