The immune system is a defense system, both children, and adult have the same reaction toward pathogen, uses multiple defense mechanisms evolved to recognize and neutralize pathogens also have the ability to distinguish self from non-self cells, but in case of Varicella-zoster virus (VZV) that cause chicken pox, the immune system reacts differently in young healthy adult usually have an aggressive reaction serious complications can lead to death, compare with children infection is usually mild. This overview illustrates the chickenpox and difference of immune response between the children and young adult toward infection with the varicella-zoster virus.
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Alaa A Elnour (2018) studied this question.
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