Key result
Prior SARS-CoV-2 infection was not associated with death, major adverse cardiovascular events, or rehospitalization within 30 days of elective major noncardiac surgery (aRR 0.91; 95% CI 0.68-1.21).
Why the study?
Evidence was needed to inform preoperative risk assessment and surgical care planning for patients who have had SARS-CoV-2 infection and are awaiting elective surgery.
Does prior SARS-CoV-2 infection increase the risk of death, major adverse cardiovascular events, or rehospitalization in adults undergoing elective major noncardiac surgery?
Cohort (n=71,144)
Does prior SARS-CoV-2 infection increase the risk of death, major adverse cardiovascular events, or rehospitalization in adults undergoing elective major noncardiac surgery?
Relative Risk: 0.91 (95% CI 0.68–1.21)
Prior SARS-CoV-2 infection within 6 months of elective major noncardiac surgery was not associated with an increased risk of 30-day postoperative death, major adverse cardiovascular events, or rehospitalization.
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Does not support delaying elective surgery after prior infection; leaves open confirmation in prospective trials.
Quinn et al. (2022) conducted a cohort in Elective major noncardiac surgery (n=71,144). Prior SARS-CoV-2 infection vs. Negative SARS-CoV-2 test result was evaluated on Composite of death, major adverse cardiovascular events, and all-cause rehospitalization within 30 days after surgery (aRR 0.91, 95% CI 0.68-1.21). Prior SARS-CoV-2 infection was not associated with death, major adverse cardiovascular events, or rehospitalization within 30 days of elective major noncardiac surgery (aRR 0.91; 95% CI 0.68-1.21).
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