Case Report (n=1)
Radiotherapy combined with immunotherapy can provide durable palliation and long-term survival in rare cases of isolated cardiac metastasis, though it carries risks of significant cardiac toxicity.
Hypothesis-generating for radiation plus immunotherapy in isolated cardiac metastases; should not change practice without prospective data.
Cardiac metastases are a rare clinical entity and they generally portend a poor prognosis. Management is generally directed toward symptom control and maintaining cardiac function; however, long-term survival is rare. Here, we report a case of isolated metastatic urothelial cell carcinoma to the right ventricle that was functionally limiting the patient. The metastasis was successfully palliated for 17 months following radiation and immune therapy; however, disease progression in and around his heart ultimately led to a cardiac arrest.
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Arscott et al. (2018) conducted a case report in Metastatic urothelial cell carcinoma to the right ventricle (n=1). Radiation and immune therapy (atezolizumab) was evaluated on Survival.
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