Key result
Chemotherapy relieves symptoms from rare right ventricular metastasis in transitional cell bladder cancer.
Why the study?
Cardiac metastases from transitional cell carcinoma of the bladder are rare and rarely reported, with limited data on effective treatment.
Case Report (n=1)
This case highlights the rare occurrence of cardiac metastasis from transitional cell bladder cancer and demonstrates that chemotherapy can provide symptomatic improvement.
May support chemotherapy for rare symptomatic cardiac metastases; hypothesis-generating and should not yet change practice.
Although it is common to find metastases of transitional cell carcinoma of the bladder to the lymph nodes, lung, bone, and liver, cardiac metastases have only been rarely reported. We report a case of symptomatic metastasis of transitional cell cancer to the right ventricle. A 59-year-old man with a history of transitional cell bladder cancer status post cystectomy and chemotherapy, with neobladder placement, presented with hematuria, shortness of breath, murmur, and evidence of right-sided heart failure. On imaging workup, including transthoracic echocardiography and cardiac computed tomography, we found a large right ventricular mass. A review of the literature showed that there are only 9 cases of cardiac metastasis from transitional cell cancer reported; however, our case is unique because it is the only reported case of symptomatic improvement due to effective treatment with chemotherapy.
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Doshi et al. (2010) conducted a case report in Cardiac metastasis from transitional cell bladder cancer (n=1). Chemotherapy was evaluated on Symptomatic improvement. Chemotherapy effectively treated a rare case of symptomatic right ventricular metastasis from transitional cell bladder cancer, leading to symptomatic improvement.
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