Why the study?
Cardiac metastasis is a rare fatal event, and an intracavitary right tumor mainly in the ventricle is difficult to manage.
Does transcoronary tumor embolization followed by cardiac radiotherapy improve symptoms and local control in patients with severe right cardiac metastasis after surgical failure?
Does transcoronary tumor embolization followed by cardiac radiotherapy improve symptoms and local control in patients with severe right cardiac metastasis after surgical failure?
Transcoronary tumor embolization followed by moderate-dose radiotherapy may offer a safe and effective salvage treatment for large right heart metastases after surgical failure.
May support salvage embolization-radiotherapy in rare refractory cases; hypothesis-generating and requires prospective validation.
PURPOSE: Cardiac metastasis is a rare fatal event. An intracavitary right tumor mainly in the ventricle is difficult to manage. Literature reports suggest that cardiac surgery in oligometastatic patients could offer median survival of 1 year. We investigated salvage treatment comprising transcoronary tumor embolization followed 15 days later by cardiac radiotherapy (40.5 Gy/15 fractions). CASES: We report two cases of severe right cardiac metastasis with a history of abdominal cancer managed by this salvage treatment following residual cardiac mass after previous cardiac surgery. CONCLUSION: Both symptomatic patients improved progressively and were locally controlled for at least 1 year without toxicity.
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Delanian et al. (2021) studied this question.
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