Key result
Heart rate variability components (AF and LF) were significantly lower in patients with diabetes alone or diabetes with severe ischemic heart disease compared to healthy controls.
Why the study?
Does the presence and severity of ischemic heart disease affect heart rate variability in patients with diabetes mellitus?
Population
71 subjects including 21 healthy controls, 17 diabetic patients without ischemic heart disease, and 33…
Comparison
Diabetes mellitus with or without ischemic heart… vs Healthy control subjects
Design
Cross-sectional
Authors
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Reduced HRV in diabetes may signal autonomic dysfunction warranting monitoring; cross-sectional data leave open independent IHD severity effects.
Observational (n=71)
Does the presence and severity of ischemic heart disease affect heart rate variability in patients with diabetes mellitus?
Heart rate variability in diabetic patients with severe ischemic heart disease is reduced due to a combination of diabetic neuropathy and a decline in parasympathetic tone from myocardial injury.
Fujimoto et al. (1996) conducted an observational in Diabetes Mellitus and Ischemic Heart Disease (n=71). Diabetes mellitus with or without ischemic heart disease vs. Healthy control subjects was evaluated on Heart rate variability (spectral variables of AF, LF, HF components and LF/HF ratio). Heart rate variability components (AF and LF) were significantly lower in patients with diabetes alone or diabetes with severe ischemic heart disease compared to healthy controls.
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