Key result
Patients on continuous ambulatory peritoneal dialysis had normal atrial natriuretic factor levels (8.3 vs 7.3 pmol/L, NS), whereas levels were significantly elevated in hemodialysis patients.
Why the study?
How do levels of atrial natriuretic factor and the renin system compare between patients on continuous ambulatory peritoneal dialysis, hemodialysis, and normal controls?
Observational (n=30)
How do levels of atrial natriuretic factor and the renin system compare between patients on continuous ambulatory peritoneal dialysis, hemodialysis, and normal controls?
Absolute Event Rate: 8.3% vs 7.3%
p-value: p=NS
Patients on continuous ambulatory peritoneal dialysis maintain normal levels of atrial natriuretic factor, unlike hemodialysis patients who exhibit elevated levels prior to dialysis.
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Preserved ANF in CAPD but elevated in HD may reflect modality differences in volume control; hypothesis-generating and requires prospective confirmation.
Mora‐Macía et al. (1993) conducted an observational in End-stage renal disease on dialysis (n=30). Continuous ambulatory peritoneal dialysis (CAPD) vs. Chronic hemodialysis (HD) and healthy controls was evaluated on Atrial natriuretic factor (ANF) levels (p=NS). Patients on continuous ambulatory peritoneal dialysis had normal atrial natriuretic factor levels (8.3 vs 7.3 pmol/L, NS), whereas levels were significantly elevated in hemodialysis patients.
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