Key result
The Segmented-Beat Modulation Method (SBMM) estimated ECG with significantly lower estimation errors than a standard template method for QRS (176-232µV vs 215-496µV) and TUP segments (79-499µV vs 93-1056µV).
The Segmented-Beat Modulation Method provides a more robust approach to filtering noisy ECG recordings while preserving physiological variability compared to standard template methods.
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SBMM may improve ECG denoising in noisy recordings; leaves open effects on clinical interpretation or outcomes.
Clinical utility of an electrocardiogram (ECG) affected by too high levels of noise such as baseline wanders, electrode motion artifacts, muscular artifacts and power-line interference may be jeopardized if not opportunely processed. Template-based techniques have been proposed for ECG estimation from noisy recordings, but usually they do not reproduce physiological ECG variability, which, however, provides clinically useful information on the patient's health. Thus, this study proposes the Segmented-Beat Modulation Method (SBMM) as a new template-based filtering procedure able to reproduce ECG variability, and assesses SBMM robustness to the aforementioned noises in comparison to a standard template method (STM). SBMM performs a unique ECG segmentation into QRS segment and TUP segment, and successively modulates/demodulates (by stretching or compressing) the former segments in order to adaptively adjust each estimated beat to its original morphology and duration. Consequently, SBMM estimates ECG with significantly lower estimation errors than STM when applied to recordings affected by various levels of the considered noises (SBMM: 176-232µV and 79-499µV; STM: 215-496µV and 93-1056µV, for QRS and TUP segments, respectively). Thus, SBMM is able to reproduce ECG variability and is more robust to noise than STM.
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Agostinelli et al. (2016) studied ECG affected by noise. Segmented-Beat Modulation Method (SBMM) vs. Standard template method (STM) was evaluated on Estimation errors for QRS and TUP segments. The Segmented-Beat Modulation Method (SBMM) estimated ECG with significantly lower estimation errors than a standard template method for QRS (176-232µV vs 215-496µV) and TUP segments (79-499µV vs 93-1056µV).
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