The chiral oxazaphospholidine–borane complex 2 was used as catalyst (2 mol %) in asymmetric reduction of ketones by borane with an enantioselectivity ranging from 33 to 92% at 110 °C and 100% conversion; under stoichiometric conditions the reduction proceeded with 99% enantiomeric excess.
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Brunel et al. (1992) studied this question.
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