Key result
Free arterial grafting resulted in similar rates of repeated revascularization and all-cause mortality compared to saphenous vein grafting at 10 years of follow-up.
Why the study?
The study was conducted to examine whether the use of free arterial grafts could reduce the need for repeated revascularization and all-cause mortality in patients undergoing coronary artery grafting.
Does free arterial grafting reduce repeated revascularization and all-cause mortality compared to saphenous vein grafting in adults undergoing isolated coronary artery bypass surgery?
Cohort (n=17,354)
Yes
Does free arterial grafting reduce repeated revascularization and all-cause mortality compared to saphenous vein grafting in adults undergoing isolated coronary artery bypass surgery?
In patients undergoing isolated coronary artery bypass grafting, the use of free arterial grafts compared to saphenous vein grafts resulted in similar long-term rates of repeated revascularization and all-cause mortality at 10 years.
Free arterial grafts were associated with similar 10-year outcomes to vein grafts in CABG; leaves open confirmation in randomized trials.
Objectives. The goal of this study was to examine whether the use of free arterial grafts could reduce the need for repeated revascularization and all-cause mortality in patients undergoing coronary artery grafting. Design. The cohort study included 17,354 consecutive adults with isolated coronary artery grafting from 2000 to 2016 in three cardiac surgery centers. Data were obtained from the Western Denmark Heart Registry. Propensity matching with 24 factors was used to establish comparable groups of patients receiving either vein grafts (n = 1019) or free arterial grafts (n = 1019) for outcome analysis. Results. The need for repeated revascularization and all-cause mortality was similar in both graft groups at 10 years of follow-up. Creatine-Kinase MB Isoenzyme >100 μg/L increased the risk of repeated revascularization rate after 1, 5 and 10 years. Conclusions. Long-term outcomes in revascularization and survival are comparable after free arterial or saphenous vein grafting.
No takes yet. Share an insight, caveat, or question.
Abromaitiene et al. (2022) conducted a cohort in Coronary artery grafting (n=17,354). Free arterial grafts vs. Saphenous vein grafts was evaluated on Repeated revascularization and all-cause mortality. Free arterial grafting resulted in similar rates of repeated revascularization and all-cause mortality compared to saphenous vein grafting at 10 years of follow-up.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: