Key result
Maternal indomethacin therapy for 8.5 weeks successfully managed twin reversed arterial perfusion sequence, resulting in the delivery of a normal live-born infant at 34 weeks.
Why the study?
Does maternal administration of indomethacin improve outcomes in twin reversed arterial perfusion (TRAP) sequence complicated by hydramnios?
Does maternal administration of indomethacin improve outcomes in twin reversed arterial perfusion (TRAP) sequence complicated by hydramnios?
Maternal administration of indomethacin may be a successful management strategy for TRAP sequence complicated by hydramnios.
May support indomethacin in TRAP with hydramnios; hypothesis-generating case report requiring prospective validation before practice change.
A case of twin reversed arterial perfusion (TRAP) sequence (acardiac twin) complicated by hydramnios was managed by maternal administration of indomethacin. Successful outcome was achieved after 8.5 weeks of therapy with delivery of a normal live-born infant at 34 weeks.
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Ash et al. (1990) studied this question. Maternal indomethacin therapy for 8.5 weeks successfully managed twin reversed arterial perfusion sequence, resulting in the delivery of a normal live-born infant at 34 weeks.
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