Key result
Left atrial volume calculation from long axis 2-chamber stacks showed a minimal mean difference of 0.01 ml compared to the short axis method, with improved intra-observer reproducibility.
Why the study?
Does left atrial volume measurement using long axis 2ch stacks improve reproducibility compared to short axis and biplane methods in volunteers?
Cross-Sectional (n=19)
No
Does left atrial volume measurement using long axis 2ch stacks improve reproducibility compared to short axis and biplane methods in volunteers?
Mean Difference: 0.01
Absolute Event Rate: 69.1% vs 69.1%
Long axis 2ch stack imaging provides an excellent, highly reproducible alternative to the short axis method for measuring left atrial volume on cardiac MRI.
May support reproducible LA volumetry on CMR in research; leaves open clinical adoption pending validation in patients.
Left atrial (LA) dilation is an important index in cardiovascular disease. The CMR volumetric short axis method is the reference imaging standard but has limited ability to define the mitral valve plane accurately. The biplane method is simpler and frequently employed in clinical settings. We hypothesized that long axis two chamber (2ch) imaging might better define left atrial boundaries.
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Posina et al. (2011) conducted a cross-sectional in Healthy volunteers (n=19). Long axis 2-chamber (2ch) stack MRI vs. Short axis method and biplane methods was evaluated on Left atrial volume measurement difference between short axis and 2ch stack methods (Mean difference 0.01 ml). Left atrial volume calculation from long axis 2-chamber stacks showed a minimal mean difference of 0.01 ml compared to the short axis method, with improved intra-observer reproducibility.
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