Key result
Exaggerated morning blood pressure surge (≥37 mm Hg) was an independent predictor of a widened frontal QRS-T angle in patients with newly diagnosed hypertension (P<.001).
Why the study?
Morning blood pressure surge plays an important role in target organ damage and MACE, but its relationship with the f(QRS-T) angle in newly diagnosed hypertension was uninvestigated.
Is high morning blood pressure surge associated with a widened frontal QRS-T angle in newly diagnosed hypertensive patients?
Observational (n=263)
Is high morning blood pressure surge associated with a widened frontal QRS-T angle in newly diagnosed hypertensive patients?
Exaggerated morning blood pressure surge is associated with a widened frontal QRS-T angle, suggesting a potential mechanism for increased ventricular arrhythmogenic risk in these patients.
May link morning BP surge to repolarization changes in hypertension; hypothesis-generating for arrhythmia risk, needs prospective confirmation.
BACKGROUND: Morning blood pressure surge (MBPS) plays an important role in target organ damage and major adverse cardiac events. The frontal QRS-T [f(QRS-T)] angle is the electrocardiographic marker and index of ventricular arrhythmogenic events. We aimed to investigate the relationship between MBPS and the f(QRS-T) angle, which is an indicator of ventricular repolarization disorder, in patients with newly diagnosed HT. METHODS: Between June 2020 and March 2021, 263 patients with newly diagnosed HT who were admitted to our outpatient clinic were prospectively included in the study. According to ambulatory blood pressure monitoring (ABPM), the patients were categorized into two groups: Group-I: low-value MBPS (<37 mm Hg), and group-II: high-value MBPS (≥37 mm Hg). The f(QRS-T) angle calculated from the 12-lead electrocardiogram and all other data were compared between the groups. According to multivariate regression analysis, T peak-end and MBPS were found to be independent predictors of the f(QRS-T) angle. CONCLUSIONS: As a result of our study, we found that the f(QRS-T) angle was widened in patients with exaggerated MBPS. The cause of increased cardiovascular outcomes in patients with exaggerated MBPS may be explained by widened in the f(QRS-T) angle that is a ventricular repolarization parameter.
No takes yet. Share an insight, caveat, or question.
Bağcı et al. (2021) conducted an observational in Newly diagnosed hypertension (n=263). High-value morning blood pressure surge (≥37 mm Hg) vs. Low-value morning blood pressure surge (<37 mm Hg) was evaluated on Frontal QRS-T angle (p=<.001). Exaggerated morning blood pressure surge (≥37 mm Hg) was an independent predictor of a widened frontal QRS-T angle in patients with newly diagnosed hypertension (P<.001).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: