Key result
A non-suture end-to-end method of vessel anastomosis using fibrin tubes was successfully verified in 134 dogs for heart revascularization.
Why the study?
Does a non-suture end-to-end vessel anastomosis using fibrin tubes enable successful heart revascularization in an experimental dog model?
Does a non-suture end-to-end vessel anastomosis using fibrin tubes enable successful heart revascularization in an experimental dog model?
Fibrin tubes offer a feasible non-suture method for coronary anastomosis in a preclinical model, potentially suitable for small-diameter vessels and acute infarction.
Supports preclinical feasibility of fibrin tube anastomosis; leaves open translation to human coronary revascularization.
In experimental work on 134 dogs, the authors succeeded in verifying a non-suture end-to-end method of vessel anastomosis for the purpose of heart revascularization. Instead of usual steel tubes, the authors used fibrin tubes which make the method more suitable for clinical use also. This method seems to be more advantageous especially for operation on coronary arteries of very small peripheral diameter and possibly for the treatment of acute infarction, too. Besides, it was proved that the best way to prevent ventricular fibrillation after revascularization is the intermittent and gradual release of the blood flow through the anastomosis. The question of possible diagnosis of an unsuccessfull operation during the postoperative course was also studied. It was found that besides electrocardiographical and coronarographical examinations, the plasma-enzyme level (especially SGOT) may be of some help in solving this question.
No takes yet. Share an insight, caveat, or question.
Bartoš et al. (2008) studied Ischemic Heart Disease (n=134). Non-suture end-to-end vessel anastomosis using fibrin tubes vs. Usual steel tubes was evaluated on Feasibility of non-suture end-to-end vessel anastomosis. A non-suture end-to-end method of vessel anastomosis using fibrin tubes was successfully verified in 134 dogs for heart revascularization.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: