Why the study?
Does excision of an acute infarct improve survival and ventricular function in a canine model of experimental myocardial infarction?
Population
20 dogs with experimental myocardial infarction induced by ligation of the anterior descending coronary artery
Comparison
Excision of the ischemic portion of the left… vs Ligation of the anterior descending coronary…
Design
Preclinical
Follow-up
3 to 5 months
Authors
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Hypothesis-generating in canine acute MI; leaves open any human translation or clinical role.
Does excision of an acute infarct improve survival and ventricular function in a canine model of experimental myocardial infarction?
In a canine model, excision of an acute myocardial infarct improves survival and preserves ventricular function compared to coronary ligation alone.
James R. Jude (1968) studied this question.
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