Why the study?
Does excision of an akinetic left ventricular segment improve haemodynamics in a canine model of myocardial infarction?
Population
25 dogs with experimentally produced myocardial infarcts (LAD ligation and agar injection) and 11 control dogs
Comparison
Excision of the akinetic segment acutely or… vs 11 control dogs
Design
Preclinical
Follow-up
1 to 6 weeks
Authors
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Excision of akinetic segments does not improve LV function in canine MI; leaves open any role in human remodeling.
Does excision of an akinetic left ventricular segment improve haemodynamics in a canine model of myocardial infarction?
In a canine model of myocardial infarction, excision of the resulting akinetic left ventricular segment did not improve cardiac haemodynamics or function.
Pairolero et al. (1972) studied this question.
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