Key result
Strenuous exercise post-MI fails to improve hemodynamics or infarct size versus rest in dogs.
Why the study?
The effects of daily strenuous physical exercise on myocardial function and infarct size after experimental myocardial infarction were unclear.
Does daily strenuous physical exercise improve myocardial function or reduce infarct size in dogs with experimental myocardial infarction?
Population
10 surviving dogs with experimental myocardial infarction
Comparison
Daily strenuous physical exercise for four weeks vs kept at rest for four weeks
Design
Experimental study in dogs
Authors
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Cautions against assuming post-MI exercise benefits from animal data; leaves open translation to human trials.
Does daily strenuous physical exercise improve myocardial function or reduce infarct size in dogs with experimental myocardial infarction?
Four weeks of strenuous physical exercise did not significantly alter myocardial function or infarct size in a canine model of experimental myocardial infarction.
Bart M. Pasternak (1973) studied Experimental Myocardial Infarction (n=10). Strenuous physical exercise vs. Rest was evaluated on Hemodynamic and pathologic parameters (left ventricular end diastolic pressure, contractile element velocity, infarct size, thickness). Four weeks of daily strenuous physical exercise in dogs after experimental myocardial infarction showed no significant differences in hemodynamic parameters or infarct size compared to rest.
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