Key result
Noncardiac surgery after drug-eluting stent implantation carried a 10% risk of perioperative complications, which did not differ significantly with perioperative clopidogrel use (10% vs 10%, P=0.90).
Why the study?
What is the frequency and risk of perioperative complications in patients undergoing noncardiac surgery after drug-eluting stent implantation?
Cohort (n=827)
No
What is the frequency and risk of perioperative complications in patients undergoing noncardiac surgery after drug-eluting stent implantation?
Absolute Event Rate: 10% vs 10%
p-value: p=0.90
Noncardiac surgery is frequently needed after DES implantation and appears to carry a low risk of stent thrombosis and perioperative complications, regardless of perioperative clopidogrel continuation.
No takes yet. Share an insight, caveat, or question.
Does not support altering perioperative clopidogrel after DES; leaves open need for randomized trials to guide practice.
Gandhi et al. (2010) conducted a cohort in Drug-eluting stent implantation (n=827). Perioperative clopidogrel vs. No perioperative clopidogrel was evaluated on Perioperative complications (p=0.90). Noncardiac surgery after drug-eluting stent implantation carried a 10% risk of perioperative complications, which did not differ significantly with perioperative clopidogrel use (10% vs 10%, P=0.90).
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