Key result
Double-lung transplantation is linked to ~4-fold higher post-operative AF risk than heart transplantation.
Why the study?
Both heart and double-lung transplantation involve pulmonary vein isolation due to suture lines, so comparing post-operative atrial arrhythmias between them provides insight into factors contributing to post-operative AF.
Does the incidence of post-operative atrial fibrillation differ between double-lung transplant and heart transplant patients?
Population
174 consecutive heart transplant patients and 122 double-lung transplant patients
Comparison
Double-lung transplant vs heart transplant
Design
Single-center retrospective record review
Authors
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Suggests tailored arrhythmia monitoring by transplant type; leaves open mechanistic and management questions for prospective validation.
Cohort (n=296)
No
Does the incidence of post-operative atrial fibrillation differ between double-lung transplant and heart transplant patients?
Absolute Event Rate: 18.9% vs 4.6%
p-value: p=< 0.001
Post-operative atrial fibrillation is significantly less common after heart transplantation compared to double-lung transplantation, suggesting cardiac autonomic denervation may have a protective effect.
Dizon et al. (2009) conducted a cohort in Heart or double-lung transplantation (n=296). Double-lung transplantation vs. Heart transplantation was evaluated on Incidence of atrial fibrillation (p=< 0.001). Post-operative atrial fibrillation was significantly more common after double-lung transplantation compared to heart transplantation (18.9% vs 4.6%; p<0.001).
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