Key result
Management of Eisenmenger syndrome in pregnancy requires a multidisciplinary team, with potential use of vasodilators, Caesarean section for termination, and epidural analgesia.
Case Report (n=1)
Highlights the therapeutic challenges and multidisciplinary management required for pregnant patients with Eisenmenger Syndrome, a condition where pregnancy is ideally contraindicated.
May support vasodilator use in Eisenmenger pregnancies; hypothesis-generating and requires prospective confirmation.
Eisenmenger Syndrome poses a hemodynamic overload and additional burden for the already compromised right ventricle. It causes right to left shunt thereby exaggerating central cyanosis, leading to various sequelae in the form of abortion, preterm labor and intrauterine fetal growth restriction. Vasodilators in the form of intravenous prostacyclin, phosphodiesterase inhibitors like sildenal and tadalal and inhaled nitric oxide during second stage of labor have been successfully used. Pregnancy is ideally contraindicated. Those continuing pregnancy must be adequately supervised by an experienced multidisciplinary team. Termination of pregnancy is done by Caesarean. Epidural analgesia is preferred.
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Kumar et al. (2021) conducted a case report in Eisenmenger Syndrome in pregnancy (n=1). Multidisciplinary management including vasodilators and Caesarean delivery was evaluated. Management of Eisenmenger syndrome in pregnancy requires a multidisciplinary team, with potential use of vasodilators, Caesarean section for termination, and epidural analgesia.
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