Key result
Higher socioeconomic deprivation was associated with a small increase in in-hospital mortality after isolated CABG in the UK (1.30% in the most deprived vs 1.15% in the least deprived).
Why the study?
The influence of socioeconomic deprivation on cardiac surgery outcomes in countries with universal healthcare systems, such as the UK, has been less extensively investigated.
Does socioeconomic deprivation worsen in-hospital survival in patients undergoing isolated CABG in a universal healthcare system?
Cohort (n=182,911)
Yes
Does socioeconomic deprivation worsen in-hospital survival in patients undergoing isolated CABG in a universal healthcare system?
Socioeconomic deprivation is associated with higher comorbidity burdens and a small decrease in in-hospital survival after CABG, even within a universal healthcare system.
Socioeconomic deprivation may warrant targeted risk mitigation in UK CABG patients; leaves open whether universal healthcare fully mitigates outcome disparities.
OBJECTIVES: Previous studies have identified a correlation between socioeconomic deprivation and poorer outcomes following cardiac surgery in the USA, where healthcare is predominantly delivered through private system. However, the influence of socioeconomic deprivation in countries with universal healthcare systems, such as the UK, has been less extensively investigated. Therefore, we used the index of multiple deprivation (IMD) to evaluate the impact of socioeconomic status on early clinical outcomes following coronary artery bypass grafting (CABG) in the UK. METHODS: All patients who underwent elective/urgent isolated CABG between 2008 and 2019 in the UK were included. The IMD, along with other perioperative characteristics, were incorporated into a regression model to determine factors associated with in-hospital mortality. RESULTS: The analysis included 182 911 patients (median age: 67.3 years, 82.13% male). Patients were categorized into five groups based on IMD, 1: most deprived to 5 the least: 1 = 30 564, 2 = 30 815, 3 = 59 161, 4 = 31 891 and 5 = 30 480. Patients from the most socioeconomically deprived areas exhibited markedly higher rates of comorbidities and risk factors such as diabetes and had a higher rate of urgent surgical intervention. There is a small increase in in-hospital mortality when socioeconomic status declined, with rates of 1.30, 1.30, 1.24, 1.14 and 1.15% for group 1-5, respectively. Socioeconomic deprivation, particularly in income and education, was associated with an increase in in-hospital survival. CONCLUSIONS: Socioeconomic deprivation, particularly in income and education, is associated with higher burdens of comorbidity and a small decrease in-hospital survival after CABG in the UK. This suggests that these factors may play a critical role in clinical outcomes even in a universal healthcare system.
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Chan et al. (2025) conducted a cohort in isolated coronary artery bypass grafting (CABG) (n=182,911). Socioeconomic deprivation vs. Least socioeconomically deprived areas was evaluated on In-hospital mortality. Higher socioeconomic deprivation was associated with a small increase in in-hospital mortality after isolated CABG in the UK (1.30% in the most deprived vs 1.15% in the least deprived).
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