What is the clinical evidence from this study?

Study design: Case Report. Population: Coronary artery disease (n=1). Intervention: Rotational atherectomy. Primary outcome: Clinical and postmortem outcome.

What question did this study set out to answer?

To evaluate the clinical progression and postmortem pathological findings associated with the no-reflow phenomenon after coronary rotational atherectomy.

August 1, 1996Southern Medical Journal

Clinical and Postmortem Outcome of ‘No–Reflow’ Phenomenon in a Patient Treated With Rotational Atherectomy

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Key result

Rotational atherectomy can cause clinically significant atheroemboli and the 'no-reflow' phenomenon, as demonstrated in a fatal case.

Key Points

To evaluate the clinical progression and postmortem pathological findings associated with the no-reflow phenomenon after coronary rotational atherectomy.
Clinical and postmortem evaluation of a 77-year-old female patient (N=1) who developed no-reflow following circumflex artery rotational atherectomy with a Rotablator device.
Gross and microscopic autopsy examination of cardiac tissue after subsequent balloon angioplasty of the right coronary artery and fatal acute vessel closure.
Rotational atherectomy triggered an immediate no-reflow complication, followed 11 days later by fatal acute vessel closure following right coronary angioplasty.
Postmortem analysis revealed gross evidence of recent posterior myocardial infarction alongside widespread atheroemboli physically occluding myocardial arterioles.

Study Design

Type

Case Report (n=1)

Structured PICO

Population

A 77-year-old woman who underwent rotational atherectomy complicated by no-reflow and subsequent death.

Intervention

Rotational atherectomy using the Rotablator device

Outcome

Clinical outcome and postmortem findingssafety

Rotational atherectomy can cause clinically significant atheroemboli leading to the no-reflow phenomenon and adverse outcomes.

Discussion

No takes yet. Share an insight, caveat, or question.

Implication

May signal need for caution with rotational atherectomy; leaves open the frequency and preventability of atheroembolic no-reflow.

Cite This Study

Palko et al. (1996) conducted a case report in Coronary artery disease (n=1). Rotational atherectomy was evaluated on Clinical and postmortem outcome. Rotational atherectomy can cause clinically significant atheroemboli and the 'no-reflow' phenomenon, as demonstrated in a fatal case.

synapsesocial.com/papers/6a9ba8e5d8d8bde79ebb05fa https://doi.org/10.1097/00007611-199608000-00015

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Clinical and Postmortem Outcome of ‘No–Reflow’ Phenomenon in a Patient Treated With Rotational Atherectomy

Key Points

Study Design

Structured PICO

Discussion

Implication

Cite This Study

Clinical and Postmortem Outcome of ‘No–Reflow’ Phenomenon in a Patient Treated With Rotational Atherectomy

Key Points

Study Design

Structured PICO

Discussion

Implication

Cite This Study

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