Key result
An angiosarcoma can arise in a non-functioning arteriovenous fistula even in a patient without a kidney transplant or chronic immunosuppressive therapy.
Case Report (n=1)
Clinicians should be aware that angiosarcomas can arise in arteriovenous fistulas even in the absence of chronic immunosuppression.
Angiosarcoma should be considered in non-functioning AV fistulas even without immunosuppression; this case extends the spectrum and leaves open the need for surveillance data.
Angiosarcomas are relatively rare and account for only 1% of all sarcomas. They arise from endothelial cells of blood or lymph vessels. They are usually highly aggressive and long term outcome is poor with an overall 5-year survival rate of 10-20%. We report the case of a 80-year old man with an angiosarcoma arising in a non-functioning arteriovenous fistula. Angiosarcomas arising in an arteriovenous fistula are very rare and only eleven cases were found in the literature. In nine cases (82%) chronic immunosuppression, taken for renal transplant, was one of the causing factors. Our patient however did not receive a kidney transplant and was not on immunosuppressive therapy. Clinicians should be aware that an angiosarcoma can arise in an arteriovenous fistula even without chronic immunosuppression.
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Demey et al. (2014) conducted a case report in Angiosarcoma arising in an arteriovenous fistula (n=1). Arteriovenous fistula without chronic immunosuppression was evaluated. An angiosarcoma can arise in a non-functioning arteriovenous fistula even in a patient without a kidney transplant or chronic immunosuppressive therapy.
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