Key result
Rabbit cardiac myosin has a molecular weight of ~4.7 x 10^5 and displays similar physical and chemical properties to skeletal myosin, despite having approximately one-third the specific ATPase activity.
Population
Rabbit cardiac myosin isolated from frozen tissue
Comparison
Physical and chemical characterization vs Skeletal myosin
Design
Preclinical
Authors
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Rabbit cardiac-skeletal myosin similarities with ATPase divergence are hypothesis-generating; leaves open isoform roles in human cardiac energetics.
Rabbit cardiac myosin is structurally similar to skeletal myosin but possesses significantly lower ATPase activity.
Wolodko et al. (1975) studied this question. Rabbit cardiac myosin vs. Skeletal myosin was evaluated on Physical and chemical properties (ATPase activity, molecular weight, secondary structure). Rabbit cardiac myosin has a molecular weight of ~4.7 x 10^5 and displays similar physical and chemical properties to skeletal myosin, despite having approximately one-third the specific ATPase activity.
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