Key result
Voltage-gated Na+ channel beta subunits are multifunctional components that mediate signaling processes and may prove useful in disease diagnosis and therapy.
Design
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Beta subunits may inform arrhythmia management; leaves open their diagnostic/therapeutic utility pending prospective studies.
Voltage-gated sodium channel beta subunits play multifunctional roles in various pathophysiologies, including cardiac arrhythmias, and may serve as potential diagnostic and therapeutic targets.
Brackenbury et al. (2008) conducted a review in Epilepsy, cardiac arrhythmia, multiple sclerosis, periodic paralysis, migraine, neuropathic and inflammatory pain, Huntington's disease, and cancer. Voltage-gated Na+ channel beta subunits was evaluated. Voltage-gated Na+ channel beta subunits are multifunctional components that mediate signaling processes and may prove useful in disease diagnosis and therapy.
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