Validity of Tier 1 Modelling Tools and Impacts on Exposure Assessments within REACH Registrations—ETEAM Project, Validation Studies and Consequences

odels) project that evaluated exposure assessment tools under the European REACH regulation (Registration, Evaluation, Authorisation and Restriction of Chemicals), (but next to the ETEAM project-as a project publicly funded by the German Federal Institute for Occupational Safety and Health (BAuA)-it is a rather new development that research groups from universities in Europe, but also internationally, investigated this issue. These other studies focused not only on REACH tier 1 tools but also investigated other tools and aspects of tool validity. This paper tries to summarise the major findings of studies that explored the different issues of tool validity by focusing on the scientific outcomes and the exposure on the science community. On the other hand, this publication aims to provide guidance on the choice and use of tools, addressing the needs of tool users. The consequences of different stakeholders under REACH are discussed from the results of the validation studies. The major stakeholders are: (1) REACH registrants or applicants for REACH authorisations, meaning those companies, consortia or associations who are subject to REACH; (2) Evaluating authorities within the scope of REACH, meaning the ECHA (European Chemicals Agency) secretariat and committees, but also the competent authorities of the member states or the European Union; (3) Developers of the different models and tools; (4) Users of the different models and tools.