Key result
Symptomatic patients with prior CABG receiving medical therapy had a higher prevalence of type C coronary artery disease (80.6% vs 60.1%, P<0.001) and diffuse lesions than those receiving PCI.
Why the study?
The study was conducted to explore the coronary angiography characteristics of symptomatic patients with prior CABG.
What are the differences in coronary angiography characteristics between symptomatic prior CABG patients treated with medical therapy versus percutaneous coronary intervention?
Observational (n=993)
No
What are the differences in coronary angiography characteristics between symptomatic prior CABG patients treated with medical therapy versus percutaneous coronary intervention?
Absolute Event Rate: 80.6% vs 60.1%
p-value: p=<0.001
Symptomatic post-CABG patients managed with medical therapy alone are more likely to have complex, diffuse type C coronary lesions compared to those undergoing PCI.
Objectives. The target of this study was to explore the coronary angiography characteristics for symptomatic patients with prior coronary artery bypass graft (CABG). Methods. Between 2009 and 2017, 993 patients who had undergone CABG but subsequently suffered recurrent symptoms in Beijing Anzhen Hospital were selected for this study and divided into either medical therapy (MT) group (n = 351) or percutaneous coronary intervention (PCI) group (n = 642) based on the treatment. Clinical data were analyzed between two groups. Results. Patients in the MT group were older and more likely to have chronic lung disease (6.6% vs 3.4%, P=0.026 ) while patients in the PCI group were more likely to have prior MI (8.8% vs 17.0%, P<0.001 ). In the MT group, 54.4% of patients had newly developed lesions both in the graft and native coronary artery while 58.1% in the PCI group ( P=0.003 ), and in the MT group, 80.6% had type C coronary artery disease while 60.1% in the PCI group ( P<0.001 ). Patients in the MT group presented higher proportion of diffuse lesions (49.3% vs 15.0%, P<0.001 ) in native coronary arteries. Conclusion. Patients receiving MT (35.3%) likely had occluded grafts and type C coronary artery disease featuring as diffuse lesions.
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Ma et al. (2019) conducted an observational in Symptomatic patients with prior coronary artery bypass graft (CABG) (n=993). Medical therapy vs. Percutaneous coronary intervention (PCI) was evaluated on Type C coronary artery disease (p=<0.001). Symptomatic patients with prior CABG receiving medical therapy had a higher prevalence of type C coronary artery disease (80.6% vs 60.1%, P<0.001) and diffuse lesions than those receiving PCI.
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