Key result
Hypertensive patients demonstrated similar patterns of spontaneously occurring sympathetic activity and responses to various manoeuvres in peripheral nerves compared to normotensive controls.
Why the study?
Does sympathetic activity in peripheral nerves differ between hypertensive and normotensive subjects?
Observational
Does sympathetic activity in peripheral nerves differ between hypertensive and normotensive subjects?
The basic mechanisms controlling sympathetic nerve activity in muscle and skin appear to be similar in hypertensive and normotensive individuals.
Answers are grounded in this paper and cite their sources.
Supports preserved peripheral sympathetic control in hypertension; hypothesis-generating for central mechanisms and needs prospective validation.
In hypertensive patients the general pattern of spontaneously occurring sympathetic activity (SA) as well as the sympathetic responses to various manoeuvres are similar to those of the normotensive controls. 2. This suggests that the multi-unit SA recorded in muscle and skin nerves of hypertensive patients are made up of impulses from the same fibre populations as in normotensive subjects and that the outflow of these impulses is controlled by similar mechanisms in the two groups. 3. More quantitative evidence obtained under standardized external conditions is necessary before it can be decided whether there is an increased strength of the sympathetic outflow to the skin in hypertensive patients.
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Wallin et al. (1973) conducted an observational in Hypertension. Hypertension vs. Normotensive controls was evaluated on Sympathetic activity pattern and responses to manoeuvres. Hypertensive patients demonstrated similar patterns of spontaneously occurring sympathetic activity and responses to various manoeuvres in peripheral nerves compared to normotensive controls.
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